A fluorescent activatable probe for imaging intracellular Mg2+?.
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ABSTRACT:
SUBMITTER: Treadwell R
PROVIDER: S-EPMC5789582 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
A fluorescent activatable probe for imaging intracellular Mg<sup>2+</sup> .
Treadwell Ryan R de Moliner Fabio F Subiros-Funosas Ramon R Hurd Toby T Knox Kirsten K Vendrell Marc M
Organic & biomolecular chemistry 20180101 2
An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg<sup>2+</sup> without interference from Ca<sup>2+</sup> is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg<sup>2+</sup> due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core. ...[more]
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