Ontology highlight
ABSTRACT:
SUBMITTER: Liang Y
PROVIDER: S-EPMC5790352 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Liang Yiran Y Li Yaming Y Song Xiaojin X Zhang Ning N Sang Yuting Y Zhang Hanwen H Liu Ying Y Chen Bing B Zhao Wenjing W Wang Lijuan L Guo Renbo R Yu Zhigang Z Yang Qifeng Q
Cancer biology & therapy 20180102 2
Recent studies have shown that long non-coding RNAs (lncRNAs) are involved in a number of biological processes; however, further study is still warranted to comprehensively reveal their functions. In this study, we showed that the lncRNA in non-homologous end joining (NHEJ) pathway 1 (LINP1) was related to breast cancer cell proliferation, metastasis and chemoresistance. Loss- and gain-of function studies were used to assess the role of LINP1 in promoting breast cancer progression. LINP1 knockdo ...[more]