Ontology highlight
ABSTRACT:
SUBMITTER: Toyoshima O
PROVIDER: S-EPMC5790512 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Toyoshima Osamu O Tanikawa Chizu C Yamamoto Ryuta R Watanabe Hidenobu H Yamashita Hiroharu H Sakitani Kosuke K Yoshida Shuntaro S Kubo Michiaki M Matsuo Keitaro K Ito Hidemi H Koike Kazuhiko K Seto Yasuyuki Y Matsuda Koichi K
Oncotarget 20171214 3
SNP rs2294008 in <i>Prostate Stem Cell Antigen</i> (<i>PSCA</i>) and decreased <i>PSCA</i> expression are associated with gastric cancer. The objective of this study is to investigate the role of rs2294008 and <i>PSCA</i> expression in the gastritis-gastric cancer carcinogenic pathway. We conducted a case-control association study of <i>H. pylori</i>-infected gastritis and gastric cancer. rs2294008 was associated with the progression to chronic active gastritis (<i>P =</i> 9.4 × 10<sup>-5</sup>; ...[more]