Ontology highlight
ABSTRACT:
SUBMITTER: Wong HL
PROVIDER: S-EPMC5793777 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Wong Hui-Li HL Yang Kevin C KC Shen Yaoqing Y Zhao Eric Y EY Loree Jonathan M JM Kennecke Hagen F HF Kalloger Steve E SE Karasinska Joanna M JM Lim Howard J HJ Mungall Andrew J AJ Feng Xiaolan X Davies Janine M JM Schrader Kasmintan K Zhou Chen C Karsan Aly A Jones Steven J M SJM Laskin Janessa J Marra Marco A MA Schaeffer David F DF Gorski Sharon M SM Renouf Daniel J DJ
Cold Spring Harbor molecular case studies 20180201 1
Pancreatic neuroendocrine tumors (PNETs) are a genomically and clinically heterogeneous group of pancreatic neoplasms often diagnosed with distant metastases. Recurrent somatic mutations, chromosomal aberrations, and gene expression signatures in PNETs have been described, but the clinical significance of these molecular changes is still poorly understood, and the clinical outcomes of PNET patients remain highly variable. To help identify the molecular factors that contribute to PNET progression ...[more]