Ontology highlight
ABSTRACT:
SUBMITTER: Severson TM
PROVIDER: S-EPMC5797120 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Nature communications 20180202 1
Male breast cancer (MBC) is rare and poorly characterized. Like the female counterpart, most MBCs are hormonally driven, but relapse after hormonal treatment is also noted. The pan-hormonal action of steroid hormonal receptors, including estrogen receptor alpha (ERα), androgen receptor (AR), progesterone receptor (PR), and glucocorticoid receptor (GR) in this understudied tumor type remains wholly unexamined. This study reveals genomic cross-talk of steroid hormone receptor action and interplay ...[more]