Alteration of putaminal fractional anisotropy in Parkinson's disease: a longitudinal diffusion kurtosis imaging study.
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ABSTRACT:
SUBMITTER: Surova Y
PROVIDER: S-EPMC5799343 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Publications
Alteration of putaminal fractional anisotropy in Parkinson's disease: a longitudinal diffusion kurtosis imaging study.
Surova Yulia Y Nilsson Markus M Lampinen Björn B Lätt Jimmy J Hall Sara S Widner Håkan H van Westen Danielle D Hansson Oskar O
Neuroradiology 20180124 3
<h4>Purpose</h4>In Parkinson's disease (PD), pathological microstructural changes occur that may be detected using diffusion magnetic resonance imaging (dMRI). However, there are few longitudinal studies that explore the effect of disease progression on diffusion indices.<h4>Methods</h4>We prospectively included 76 patients with PD and 38 healthy controls (HC), all of whom underwent diffusion kurtosis imaging (DKI) as part of the prospective Swedish BioFINDER study at baseline and 2 years later. ...[more]
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