Ontology highlight
ABSTRACT:
SUBMITTER: Bragg PE
PROVIDER: S-EPMC5800402 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Journal of agricultural and food chemistry 20171205 49
Biosynthesis of the dihydrogenated forms of ergot alkaloids is of interest because many of the ergot alkaloids used as pharmaceuticals may be derived from dihydrolysergic acid (DHLA) or its precursor dihydrolysergol. The maize (Zea mays) ergot pathogen Claviceps gigantea has been reported to produce dihydrolysergol, a hydroxylated derivative of the common ergot alkaloid festuclavine. We hypothesized expression of C. gigantea cloA in a festuclavine-accumulating mutant of the fungus Neosartorya fu ...[more]