Ontology highlight
ABSTRACT:
SUBMITTER: Coppens V
PROVIDER: S-EPMC5800540 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
PloS one 20180206 2
Pancreas injury by partial duct ligation (PDL) activates beta cell differentiation and proliferation in adult mouse pancreas but remains controversial regarding the anticipated increase in beta cell volume. Several reports unable to show beta cell volume augmentation in PDL pancreas used automated digital image analysis software. We hypothesized that fully automatic beta cell morphometry without manual micrograph artifact remediation introduces bias and therefore might be responsible for reporte ...[more]