Ontology highlight
ABSTRACT:
SUBMITTER: Cassar M
PROVIDER: S-EPMC5802784 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Cassar Marlène M Sunderhaus Elizabeth E Wentzell Jill S JS Kuntz Sara S Strauss Roland R Kretzschmar Doris D
Scientific reports 20180206 1
Protein kinase A (PKA) has been shown to play a role in a plethora of cellular processes ranging from development to memory formation. Its activity is mediated by the catalytic subunits whereby many species express several paralogs. Drosophila encodes three catalytic subunits (PKA-C1-3) and whereas PKA-C1 has been well studied, the functions of the other two subunits were unknown. PKA-C3 is the orthologue of mammalian PRKX/Pkare and they are structurally more closely related to each other than t ...[more]