Comprehensive profiling of prostaglandins in human ovarian follicular fluid using mass spectrometry.
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ABSTRACT:
SUBMITTER: Pier B
PROVIDER: S-EPMC5803327 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
Comprehensive profiling of prostaglandins in human ovarian follicular fluid using mass spectrometry.
Pier Bruce B Edmonds Johnathan W JW Wilson Landon L Arabshahi Alireza A Moore Ray R Bates G Wright GW Prasain Jeevan K JK Miller Michael A MA
Prostaglandins & other lipid mediators 20171109
Prostaglandins are formed by enzymatic and non-enzymatic mechanisms. They have been detected in human ovarian follicular fluid (HFF), a medium rich in growth factors and nutrients important for oocyte growth and fertility. However, the comprehensive identification of HFF prostaglandins has not been addressed. Here we use hybrid triple quadrupole time-of-flight and triple quadrupole mass spectrometers to comprehensively analyze prostaglandins in HFF. We identified PGE1, PGE2, PGF2α, and other pro ...[more]
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