Repurposing of Kinase Inhibitors as Broad-Spectrum Antiviral Drugs.
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ABSTRACT:
SUBMITTER: Schor S
PROVIDER: S-EPMC5804095 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Publications
Repurposing of Kinase Inhibitors as Broad-Spectrum Antiviral Drugs.
Schor Stanford S Einav Shirit S
DNA and cell biology 20171117 2
The high cost of drug development and the narrow spectrum of coverage typically provided by direct-acting antivirals limit the scalability of this antiviral approach. This review summarizes progress and challenges in the repurposing of approved kinase inhibitors as host-targeted broad-spectrum antiviral therapies. ...[more]
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