Ontology highlight
ABSTRACT:
SUBMITTER: Ritter JL
PROVIDER: S-EPMC5805002 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Journal of cell death 20180103
<i>Neisseria gonorrhoeae</i>, the human obligate pathogen responsible for the sexually transmitted disease gonorrhea, has evolved several mechanisms to evade the host immune response. One such mechanism is the modulation of host cell death pathways. In this study, we defined cell death pathways induced by <i>N gonorrhoeae</i> in human monocyte-derived macrophages (MDMs). In a dose-dependent manner, <i>N gonorrhoeae</i> stimulation of MDMs resulted in caspase 1 and 4-dependent cell deaths, indica ...[more]