Ontology highlight
ABSTRACT:
SUBMITTER: Mazzon M
PROVIDER: S-EPMC5805360 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Mazzon Michela M Castro Cecilia C Thaa Bastian B Liu Lifeng L Mutso Margit M Liu Xiang X Mahalingam Suresh S Griffin Julian L JL Marsh Mark M McInerney Gerald M GM
PLoS pathogens 20180129 1
Virus reprogramming of cellular metabolism is recognised as a critical determinant for viral growth. While most viruses appear to activate central energy metabolism, different viruses have been shown to rely on alternative mechanisms of metabolic activation. Whether related viruses exploit conserved mechanisms and induce similar metabolic changes is currently unclear. In this work we investigate how two alphaviruses, Semliki Forest virus and Ross River virus, reprogram host metabolism and define ...[more]