Ontology highlight
ABSTRACT:
SUBMITTER: Manolio TA
PROVIDER: S-EPMC5805563 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Clinical pharmacology and therapeutics 20171106 3
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is one of the most devastating of adverse drug reactions (ADRs) and was, until recently, essentially unpredictable. With the discovery of several risk alleles for drug-induced SJS/TEN and the demonstration of effectiveness of screening in reducing incidence, the stage is set for implementation of preventive strategies in populations at risk. Yet much remains to be learned about this potentially fatal complication of commonly used drug ...[more]