Ontology highlight
ABSTRACT:
SUBMITTER: Badgett MJ
PROVIDER: S-EPMC5805588 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Badgett Majors J MJ Boyes Barry B Orlando Ron R
Journal of chromatography. A 20180111
A model that predicts retention for peptides using a HALO<sup>®</sup> penta-HILIC column and gradient elution was created. Coefficients for each amino acid were derived using linear regression analysis and these coefficients can be summed to predict the retention of peptides. This model has a high correlation between experimental and predicted retention times (0.946), which is on par with previous RP and HILIC models. External validation of the model was performed using a set of H. pylori sample ...[more]