Effects of the Ketogenic diet in overweight divers breathing Enriched Air Nitrox.

ABSTRACT: Central Nervous System Oxygen Toxicity (CNS-OT) is one of the most harmful effects of Enriched Air Nitrox (EAN) diving. Protective factors of the Ketogenic Diet (KD) are antioxidant activity, the prevention of mitochondrial damage and anti-inflammatory mechanisms. We aimed to investigate if a short-term KD may reduce oxidative stress and inflammation during an hyperoxic dive. Samples from six overweight divers (mean?±?SD, age: 55.2?±?4.96 years; BMI: 26.7?±?0.86?kg/m2) were obtained a) before and after a dive breathing Enriched Air Nitrox and performing 20-minute mild underwater exercise, b) after a dive (same conditions) performed after 7 days of KD. We measured urinary 8-isoprostane and 8-OH-2-deoxyguanosine and plasmatic IL-1?, IL-6 and TNF-? levels. The KD was successful in causing weight loss (3.20?±?1.31?Kgs, p?

SUBMITTER: Bosco G 

PROVIDER: S-EPMC5805750 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature