Ontology highlight
ABSTRACT:
SUBMITTER: Yu CH
PROVIDER: S-EPMC5806659 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Yu Chi Ho CH Song Dong Hyun DH Choi Jun Young JY Joe Hae Eun HE Jeong Woo Hyeon WH Hur Gyeung Haeng GH Shin Young Kee YK Jeong Seong Tae ST
Human vaccines & immunotherapeutics 20171219 2
Botulinum neurotoxins (BoNTs) are the most potent toxins to mammals. A toxoid vaccine was previously used for prevention of botulinum intoxication; however, this vaccine is no longer available. Currently, no approved botulinum vaccines are available from the Food and Drug Administration (FDA). Recently, a recombinant host cell receptor-binding subunit created for use as a potential vaccine completed phase 2 clinical trials. The current study designed a vaccine candidate against BoNT type A (BoNT ...[more]