Seroprevalence of Antibodies to Toxocara Species in the United States and Associated Risk Factors, 2011-2014.

ABSTRACT: Background:Toxocariasis results from infection with larval stages of a dog and cat intestinal nematode and causes human morbidity. The current United States estimate of Toxocara exposure is 13.9% (National Health and Nutrition Examination Survey [NHANES] III [1988-1994]). Methods:We used a multiplex bead-based assay (Tc-CTL-1MBA) with purified Toxocara canis antigen to estimate Toxocara antibody seroprevalence in serum of 13 509 persons aged ≥6 years from NHANES 2011-2014 and identified seropositivity risk factors. We tested a subset of 500 samples with the T. canis enzyme immunoassay used in NHANES III to estimate prior seroprevalence had samples from NHANES III been tested by Tc-CTL-1MBA. Results:The age-standardized estimate of Toxocara seroprevalence was 5.0% (95% confidence interval [

SUBMITTER: Liu EW 

PROVIDER: S-EPMC5806997 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature