Ontology highlight
ABSTRACT:
SUBMITTER: Razy-Krajka F
PROVIDER: S-EPMC5809146 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Razy-Krajka Florian F Gravez Basile B Kaplan Nicole N Racioppi Claudia C Wang Wei W Christiaen Lionel L
eLife 20180206
In embryos, multipotent progenitors divide to produce distinct progeny and express their full potential. In vertebrates, multipotent cardiopharyngeal progenitors produce second-heart-field-derived cardiomyocytes, and branchiomeric skeletal head muscles. However, the mechanisms underlying these early fate choices remain largely elusive. The tunicate <i>Ciona</i> emerged as an attractive model to study early cardiopharyngeal development at high resolution: through two asymmetric and oriented divis ...[more]