Ontology highlight
ABSTRACT:
SUBMITTER: Oh G
PROVIDER: S-EPMC5811577 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Nature communications 20180213 1
Circadian rhythmicity governs a remarkable array of fundamental biological functions and is mediated by cyclical transcriptomic and proteomic activities. Epigenetic factors are also involved in this circadian machinery; however, despite extensive efforts, detection and characterization of circadian cytosine modifications at the nucleotide level have remained elusive. In this study, we report that a large proportion of epigenetically variable cytosines show a circadian pattern in their modificati ...[more]