The Impact of IgG transplacental transfer on early life immunity.
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ABSTRACT:
SUBMITTER: Fouda GG
PROVIDER: S-EPMC5812294 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
The Impact of IgG transplacental transfer on early life immunity.
Fouda Genevieve G GG Martinez David R DR Swamy Geeta K GK Permar Sallie R SR
ImmunoHorizons 20180101 1
Pediatric vaccines have significantly reduced infectious disease-related infant mortality, but as protective immunity often require several infant vaccine doses; maternally-acquired antibodies are critical to protect infants during the first months of life. Consequently, immunization of pregnant women is an important strategy not only to protect mothers from infection, but also to provide immunity to young infants. Nevertheless, maternal immunization can also negatively impact early life immunit ...[more]
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