Ontology highlight
ABSTRACT:
SUBMITTER: Bhutada G
PROVIDER: S-EPMC5812513 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Bhutada Govindprasad G Kavšcek Martin M Ledesma-Amaro Rodrigo R Thomas Stéphane S Rechberger Gerald N GN Nicaud Jean-Marc JM Natter Klaus K
FEMS yeast research 20170501 3
Triacylglycerol (TAG) and glycogen are the two major metabolites for carbon storage in most eukaryotic organisms. We investigated the glycogen metabolism of the oleaginous Yarrowia lipolytica and found that this yeast accumulates up to 16% glycogen in its biomass. Assuming that elimination of glycogen synthesis would result in an improvement of lipid accumulation, we characterized and deleted the single gene coding for glycogen synthase, YlGSY1. The mutant was grown under lipogenic conditions wi ...[more]