Racial and Ethnic Composition of Cancer Clinical Drug Trials: How Diverse Are We?
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ABSTRACT:
SUBMITTER: Dickmann LJ
PROVIDER: S-EPMC5813757 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
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Racial and Ethnic Composition of Cancer Clinical Drug Trials: How Diverse Are We?
Dickmann Leslie J LJ Schutzman Jennifer L JL
The oncologist 20171219 2
Many approved drugs demonstrate different pharmacokinetics, pharmacodynamics, and/or safety across racial and ethnic groups. The primary objective of the current study was to summarize the racial and ethnic makeup of cancer clinical drug trials using cancer drugs approved by the U.S. Food and Drug Administration (FDA) between January 1, 2010, and July 31, 2016. In clinical studies used for FDA approvals, 82.3% of participants identified as white, 10.2% as Asian, 2.3% as black, and 4.7% as Hispan ...[more]
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