A multiplex serologic platform for diagnosis of tick-borne diseases.
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ABSTRACT:
SUBMITTER: Tokarz R
PROVIDER: S-EPMC5816631 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Publications
A multiplex serologic platform for diagnosis of tick-borne diseases.
Tokarz Rafal R Mishra Nischay N Tagliafierro Teresa T Sameroff Stephen S Caciula Adrian A Chauhan Lokendrasingh L Patel Jigar J Sullivan Eric E Gucwa Azad A Fallon Brian B Golightly Marc M Molins Claudia C Schriefer Martin M Marques Adriana A Briese Thomas T Lipkin W Ian WI
Scientific reports 20180216 1
Tick-borne diseases are the most common vector-borne diseases in the United States, with serology being the primary method of diagnosis. We developed the first multiplex, array-based assay for serodiagnosis of tick-borne diseases called the TBD-Serochip. The TBD-Serochip was designed to discriminate antibody responses to 8 major tick-borne pathogens present in the United States, including Anaplasma phagocytophilum, Babesia microti, Borrelia burgdorferi, Borrelia miyamotoi, Ehrlichia chaffeensis, ...[more]
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