Ontology highlight
ABSTRACT:
SUBMITTER: Lucas SK
PROVIDER: S-EPMC5817045 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Lucas Sarah K SK Yang Robert R Dunitz Jordan M JM Boyer Holly C HC Hunter Ryan C RC
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20170818 2
<h4>Background</h4>Metastasis of upper airway microbiota may have significant implications in the development of chronic lung disease. Here, we compare bacterial communities of matched sinus and lung mucus samples from cystic fibrosis (CF) subjects undergoing endoscopic surgery for treatment of chronic sinusitis.<h4>Methods</h4>Mucus from one maxillary sinus and expectorated sputum were collected from twelve patients. 16S rRNA gene sequencing was then performed on sample pairs to compare the str ...[more]