Ontology highlight
ABSTRACT:
SUBMITTER: Beier D
PROVIDER: S-EPMC5817955 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Beier Dagmar D Proescholdt Martin M Reinert Christiane C Pietsch Torsten T Jones David T W DTW Pfister Stefan M SM Hattingen Elke E Seidel Clemens C Dirven Linda L Luerding Ralf R Reijneveld Jaap J Warmuth-Metz Monika M Bonsanto Matteo M Bremer Michael M Combs Stephanie E SE Rieken Stefan S Herrlinger Ulrich U Kuntze Holger H Mayer-Steinacker Regine R Moskopp Dag D Schneider Thomas T Beringer Andreas A Schlegel Uwe U Stummer Walter W Welker Helmut H Weyerbrock Astrid A Paulsen Frank F Rutkowski Stefan S Weller Michael M Wick Wolfgang W Kortmann Rolf-Dieter RD Bogdahn Ulrich U Hau Peter P
Neuro-oncology 20180201 3
<h4>Background</h4>Medulloblastoma in adult patients is rare, with 0.6 cases per million. Prognosis depends on clinical factors and medulloblastoma entity. No prospective data on the feasibility of radiochemotherapy exist. The German Neuro-Oncology Working Group (NOA) performed a prospective descriptive multicenter single-arm phase II trial to evaluate feasibility and toxicity of radio-polychemotherapy.<h4>Methods</h4>The NOA-07 trial combined craniospinal irradiation with vincristine, followed ...[more]