Ontology highlight
ABSTRACT:
SUBMITTER: Wolpaw AJ
PROVIDER: S-EPMC5818322 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Wolpaw Adam J AJ Dang Chi V CV
Trends in cell biology 20171208 3
Links between oncogenic drivers and cancer cell metabolism have emerged over the past several decades, indicating that constitutive oncogenic growth signaling can render cancers susceptible to metabolic interventions. While significant progress has been achieved in the identification of metabolic vulnerabilities of cancer cells, the complexity of the tumor microenvironment (TME) and the dynamic nature of organismal circadian metabolism challenge the precision of targeting cancer metabolism. Here ...[more]