Ontology highlight
ABSTRACT:
SUBMITTER: Quintana MDP
PROVIDER: S-EPMC5818650 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Quintana Maria Del Pilar MDP Ch'ng Jun-Hong JH Moll Kirsten K Zandian Arash A Nilsson Peter P Idris Zulkarnain Md ZM Saiwaew Somporn S Qundos Ulrika U Wahlgren Mats M
Scientific reports 20180219 1
Naturally acquired antibodies to proteins expressed on the Plasmodium falciparum parasitized red blood cell (pRBC) surface steer the course of a malaria infection by reducing sequestration and stimulating phagocytosis of pRBC. Here we have studied a selection of proteins representing three different parasite gene families employing a well-characterized parasite with a severe malaria phenotype (FCR3S1.2). The presence of naturally acquired antibodies, impact on rosetting rate, surface reactivity ...[more]