Ontology highlight
ABSTRACT:
SUBMITTER: Ho B
PROVIDER: S-EPMC5819645 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Ho Bianca B Greenlaw Keelin K Al Tuwaijri Abeer A Moussette Sanny S Martínez Francisco F Giorgio Elisa E Brusco Alfredo A Ferrero Giovanni Battista GB Linhares Natália D ND Valadares Eugênia R ER Svartman Marta M Kalscheuer Vera M VM Rodríguez Criado Germán G Laprise Catherine C Greenwood Celia M T CMT Naumova Anna K AK
Biology of sex differences 20180220 1
<h4>Background</h4>Sexual dimorphism in DNA methylation levels is a recurrent epigenetic feature in different human cell types and has been implicated in predisposition to disease, such as psychiatric and autoimmune disorders. To elucidate the genetic origins of sex-specific DNA methylation, we examined DNA methylation levels in fibroblast cell lines and blood cells from individuals with different combinations of sex chromosome complements and sex phenotypes focusing on a single autosomal region ...[more]