Unravelling the complicated evolutionary and dissemination history of HIV-1M subtype A lineages.
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ABSTRACT:
SUBMITTER: Tongo M
PROVIDER: S-EPMC5819727 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
Unravelling the complicated evolutionary and dissemination history of HIV-1M subtype A lineages.
Tongo Marcel M Harkins Gordon W GW Dorfman Jeffrey R JR Billings Erik E Tovanabutra Sodsai S de Oliveira Tulio T Martin Darren P DP
Virus evolution 20180101 1
Subtype A is one of the rare HIV-1 group M (HIV-1M) lineages that is both widely distributed throughout the world and persists at high frequencies in the Congo Basin (CB), the site where HIV-1M likely originated. This, together with its high degree of diversity suggests that subtype A is amongst the fittest HIV-1M lineages. Here we use a comprehensive set of published near full-length subtype A sequences and A-derived genome fragments from both circulating and unique recombinant forms (CRFs/URFs ...[more]
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