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Levosulpiride-induced Movement Disorders.


ABSTRACT: We reported a series of patients who presented with LSP-induced movement disorders specifically, dyskinetic movements. We have presented one case of LSP-induced parkinsonism and summarized ten cases of LSP-induced dyskinesia. The causality of the adverse drug reaction was assessed systematically using a validated rating system, and we extensively qualified the clinical presentation of each case of dyskinesia using a clinical rating scale. We described an unusual case of acute onset LSP-induced parkinsonism in a 56-year-aged female. The mean age of ten patients of LSP-induced dyskinesia was 65.3 years (standard deviation 10.4), and 25% of patients were female. They were consuming suspected medication for a median duration of 13 months (range 1-60 months). We noted LSP-induced dyskinesia was challenging to treat as its resolution is often incomplete even with adequate treatment.

SUBMITTER: Choudhury S 

PROVIDER: S-EPMC5820749 | biostudies-literature | 2017 Oct-Dec

REPOSITORIES: biostudies-literature

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Levosulpiride-induced Movement Disorders.

Choudhury Supriyo S   Chatterjee Koustav K   Singh Ravi R   Shubham Shantanu S   Trivedi Santosh S   Chatterjee Suparna S   Kumar Hrishikesh H  

Journal of pharmacology & pharmacotherapeutics 20171001 4


We reported a series of patients who presented with LSP-induced movement disorders specifically, dyskinetic movements. We have presented one case of LSP-induced parkinsonism and summarized ten cases of LSP-induced dyskinesia. The causality of the adverse drug reaction was assessed systematically using a validated rating system, and we extensively qualified the clinical presentation of each case of dyskinesia using a clinical rating scale. We described an unusual case of acute onset LSP-induced p  ...[more]

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