Ontology highlight
ABSTRACT:
SUBMITTER: Boucherie C
PROVIDER: S-EPMC5822457 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Boucherie C C Boutin C C Jossin Y Y Schakman O O Goffinet A M AM Ris L L Gailly P P Tissir F F
Molecular psychiatry 20171219 3
The development of the cerebral cortex is a tightly regulated process that relies on exquisitely coordinated actions of intrinsic and extrinsic cues. Here, we show that the communication between forebrain meninges and apical neural progenitor cells (aNPC) is essential to cortical development, and that the basal compartment of aNPC is key to this communication process. We found that Celsr1, a cadherin of the adhesion G protein coupled receptor family, controls branching of aNPC basal processes ab ...[more]