Ontology highlight
ABSTRACT:
SUBMITTER: Kleckner IR
PROVIDER: S-EPMC5823751 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Kleckner Ian R IR Kamen Charles C Gewandter Jennifer S JS Mohile Nimish A NA Heckler Charles E CE Culakova Eva E Fung Chunkit C Janelsins Michelle C MC Asare Matthew M Lin Po-Ju PJ Reddy Pavan S PS Giguere Jeffrey J Berenberg Jeffrey J Kesler Shelli R SR Mustian Karen M KM
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20171214 4
<h4>Purpose</h4>Over half of all cancer patients receiving taxane-, platinum-, or vinca alkaloid-based chemotherapy experience chemotherapy-induced peripheral neuropathy (CIPN), which includes numbness, tingling, pain, cold sensitivity, and motor impairment in the hands and feet. CIPN is a dose-limiting toxicity, potentially increasing mortality. There are no FDA-approved drugs to treat CIPN, and behavioral interventions such as exercise are promising yet understudied. This secondary analysis of ...[more]