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Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017.

ABSTRACT: We investigated influenza A(H5N6) viruses from migratory birds in Chungnam and Gyeonggi Provinces, South Korea following a reported die-off of poultry in nearby provinces in November 2017. Genetic analysis and virulence studies in chickens and ducks identified our isolate from December 2017 as a novel highly pathogenic avian influenza virus. It resulted from reassortment between the highly virulent H5N8 strain from Korea with the N6 gene from a low-pathogenic H3N6 virus from the Netherlands.

SUBMITTER: Kim YI

PROVIDER: S-EPMC5824127 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017.

Kim Young-Il YI Si Young-Jae YJ Kwon Hyeok-Il HI Kim Eun-Ha EH Park Su-Jin SJ Robles Norbert John NJ Nguyen Hiep Dinh HD Yu Min-Ah MA Yu Kwang-Min KM Lee Youn-Jeong YJ Lee Myoung-Heon MH Choi Young Ki YK

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20180201 7

We investigated influenza A(H5N6) viruses from migratory birds in Chungnam and Gyeonggi Provinces, South Korea following a reported die-off of poultry in nearby provinces in November 2017. Genetic analysis and virulence studies in chickens and ducks identified our isolate from December 2017 as a novel highly pathogenic avian influenza virus. It resulted from reassortment between the highly virulent H5N8 strain from Korea with the N6 gene from a low-pathogenic H3N6 virus from the Netherlands. ...[more]

PMID: 29463346

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