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Body mass index and lung cancer risk: a pooled analysis based on nested case-control studies from four cohort studies.

ABSTRACT: BACKGROUND:Obesity has been proposed as a potential protective factor against lung cancer. We examined the association between BMI and lung cancer risk in a pooled analysis based on nested case-control studies from four cohort studies. METHODS:A case-control study was nested within four cohorts in USA, Europe, China and Singapore that included 4172 cases and 8471 control subjects. BMI at baseline was calculated as weight in kilograms divided by height in meters squared (kg/m2), and classified into 4 categories: underweight (BMI

SUBMITTER: Sanikini H 

PROVIDER: S-EPMC5824613 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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Body mass index and lung cancer risk: a pooled analysis based on nested case-control studies from four cohort studies.

Sanikini Harinakshi H   Yuan Jian-Min JM   Butler Lesley M LM   Koh Woon-Puay WP   Gao Yu-Tang YT   Steffen Annika A   Johansson Mattias M   Vineis Paolo P   Goodman Gary E GE   Barnett Matt J MJ   Hung Rayjean J RJ   Chen Chu C   Stücker Isabelle I  

BMC cancer 20180223 1

<h4>Background</h4>Obesity has been proposed as a potential protective factor against lung cancer. We examined the association between BMI and lung cancer risk in a pooled analysis based on nested case-control studies from four cohort studies.<h4>Methods</h4>A case-control study was nested within four cohorts in USA, Europe, China and Singapore that included 4172 cases and 8471 control subjects. BMI at baseline was calculated as weight in kilograms divided by height in meters squared (kg/m<sup>2  ...[more]

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