Ontology highlight
ABSTRACT:
SUBMITTER: Stephenson W
PROVIDER: S-EPMC5824814 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Stephenson William W Donlin Laura T LT Butler Andrew A Rozo Cristina C Bracken Bernadette B Rashidfarrokhi Ali A Goodman Susan M SM Ivashkiv Lionel B LB Bykerk Vivian P VP Orange Dana E DE Darnell Robert B RB Swerdlow Harold P HP Satija Rahul R
Nature communications 20180223 1
Droplet-based single-cell RNA-seq has emerged as a powerful technique for massively parallel cellular profiling. While this approach offers the exciting promise to deconvolute cellular heterogeneity in diseased tissues, the lack of cost-effective and user-friendly instrumentation has hindered widespread adoption of droplet microfluidic techniques. To address this, we developed a 3D-printed, low-cost droplet microfluidic control instrument and deploy it in a clinical environment to perform single ...[more]