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Circular RNAs are abundant and dynamically expressed during embryonic muscle development in chickens.

ABSTRACT: The growth and development of skeletal muscle is regulated by proteins as well as non-coding RNAs. Circular RNAs (circRNAs) are universally expressed in various tissues and cell types, and regulate gene expression in eukaryotes. To identify the circRNAs during chicken embryonic skeletal muscle development, leg muscles of female Xinghua (XH) chicken at three developmental time points 11 embryo age (E11), 16 embryo age (E16) and 1?day post hatch (P1) were performed RNA sequencing. We identified 13,377 circRNAs with 3,036 abundantly expressed and most were derived from coding exons. A total of 462 differentially expressed circRNAs were identified (fold change?>?2; q-value?

SUBMITTER: Ouyang H

PROVIDER: S-EPMC5824844 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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Circular RNAs are abundant and dynamically expressed during embryonic muscle development in chickens.

Ouyang Hongjia H Chen Xiaolan X Wang Zhijun Z Yu Jiao J Jia Xinzheng X Li Zhenhui Z Luo Wei W Abdalla Bahareldin Ali BA Jebessa Endashaw E Nie Qinghua Q Zhang Xiquan X

DNA research : an international journal for rapid publication of reports on genes and genomes 20180201 1

The growth and development of skeletal muscle is regulated by proteins as well as non-coding RNAs. Circular RNAs (circRNAs) are universally expressed in various tissues and cell types, and regulate gene expression in eukaryotes. To identify the circRNAs during chicken embryonic skeletal muscle development, leg muscles of female Xinghua (XH) chicken at three developmental time points 11 embryo age (E11), 16 embryo age (E16) and 1 day post hatch (P1) were performed RNA sequencing. We identified 13 ...[more]

PMID: 29036326

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