Characterization of KPC-Encoding Plasmids from Enterobacteriaceae Isolated in a Czech Hospital.
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ABSTRACT:
SUBMITTER: Kukla R
PROVIDER: S-EPMC5826142 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
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Characterization of KPC-Encoding Plasmids from Enterobacteriaceae Isolated in a Czech Hospital.
Kukla Rudolf R Chudejova Katerina K Papagiannitsis Costas C CC Medvecky Matej M Habalova Katerina K Hobzova Lenka L Bolehovska Radka R Pliskova Lenka L Hrabak Jaroslav J Zemlickova Helena H
Antimicrobial agents and chemotherapy 20180223 3
Ten <i>Enterobacteriaceae</i> isolates collected in a Czech hospital carried <i>bla</i><sub>KPC</sub>-positive plasmids of different sizes (∼30, ∼45, and ∼80 kb). Sequencing revealed three types of plasmids (A to C) with the Tn<i>4401a</i> transposon. Type A plasmids comprised an IncR backbone and a KPC-2-encoding multidrug resistance (MDR) region. Type B plasmids were derivatives of type A plasmids carrying an IncN3-like segment, while type C plasmids were IncP6 plasmids sharing the same KPC-2- ...[more]
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