Systemic Sclerosis Trial Design Moving Forward.
Ontology highlight
ABSTRACT:
SUBMITTER: Johnson SR
PROVIDER: S-EPMC5826575 | biostudies-literature | 2016 May-Aug
REPOSITORIES: biostudies-literature
Publications
Systemic Sclerosis Trial Design Moving Forward.
Johnson Sindhu R SR Khanna Dinesh D Allanore Yannick Y Matucci-Cerinic Marco M Furst Daniel E DE
Journal of scleroderma and related disorders 20160501 2
The 2013 ACR-EULAR classification criteria for systemic sclerosis (SSc) have shifted the construct of SSc. The new reality is that patients recruited for trials may not be so severe and not so advanced. We can now look for therapeutics that might stop disease evolution and/or prevent organ involvement. This article highlights recent advances in research methodology, and broadens the potential range of design and analytic considerations when planning a SSc trial. ...[more]
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