Ontology highlight
ABSTRACT:
SUBMITTER: Devuyst O
PROVIDER: S-EPMC5827601 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Devuyst Olivier O Pattaro Cristian C
Journal of the American Society of Nephrology : JASN 20171127 3
The identification of genetic factors associated with kidney disease has the potential to provide critical insights into disease mechanisms. Genome-wide association studies have uncovered genomic regions associated with renal function metrics and risk of CKD. <i>UMOD</i> is among the most outstanding loci associated with CKD in the general population, because it has a large effect on eGFR and CKD risk that is consistent across different ethnic groups. The relevance of <i>UMOD</i> for CKD is clea ...[more]