OrthoGNC: A Software for Accurate Identification of Orthologs Based on Gene Neighborhood Conservation.
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ABSTRACT:
SUBMITTER: Jahangiri-Tazehkand S
PROVIDER: S-EPMC5828658 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
OrthoGNC: A Software for Accurate Identification of Orthologs Based on Gene Neighborhood Conservation.
Jahangiri-Tazehkand Soheil S Wong Limsoon L Eslahchi Changiz C
Genomics, proteomics & bioinformatics 20171111 6
Orthology relations can be used to transfer annotations from one gene (or protein) to another. Hence, detecting orthology relations has become an important task in the post-genomic era. Various genomic events, such as duplication and horizontal gene transfer, can cause erroneous assignment of orthology relations. In closely-related species, gene neighborhood information can be used to resolve many ambiguities in orthology inference. Here we present OrthoGNC, a software for accurately predicting ...[more]
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