New insights into the role of angiogenin in actin polymerization.
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ABSTRACT:
SUBMITTER: Pyatibratov MG
PROVIDER: S-EPMC5828769 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
New insights into the role of angiogenin in actin polymerization.
Pyatibratov Mikhail G MG Kostyukova Alla S AS
International review of cell and molecular biology 20120101
Angiogenin is a potent stimulator of angiogenesis. It interacts with endothelial cells and induces a wide range of cellular responses initiating a process of blood vessel formation. One important target of angiogenin is endothelial cell-surface actin, and their interaction might be one of crucial steps in angiogenin-induced neovascularization. Recently, it was shown that angiogenin inhibits polymerization of G-actin and changes the physical properties of F-actin. These observations suggest that ...[more]
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