Ontology highlight
ABSTRACT:
SUBMITTER: Trier NH
PROVIDER: S-EPMC5829227 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Trier Nicole Hartwig NH Holm Bettina Eide BE Heiden Julie J Slot Ole O Locht Henning H Lindegaard Hanne H Svendsen Anders A Nielsen Christoffer Tandrup CT Jacobsen Søren S Theander Elke E Houen Gunnar G
Scientific reports 20180227 1
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. Anti-citrullinated protein antibodies (ACPA) are crucial for the serological diagnosis of RA, where Epstein-Barr virus (EBV) has been suggested to be an environmental agent in triggering the onset of the disease. This study aimed to analyse antibody reactivity to citrullinated EBV nuclear antigen-2 (EBNA-2) peptides from three different EBV strains (B95-8, GD1 and AG876) using streptavidin capture enzyme-linked immunosorbent ass ...[more]