Ontology highlight
ABSTRACT:
SUBMITTER: Lee EK
PROVIDER: S-EPMC5829317 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Lee Eugene K EK Tran David D DD Keung Wendy W Chan Patrick P Wong Gabriel G Chan Camie W CW Costa Kevin D KD Li Ronald A RA Khine Michelle M
Stem cell reports 20171012 5
Accurately predicting cardioactive effects of new molecular entities for therapeutics remains a daunting challenge. Immense research effort has been focused toward creating new screening platforms that utilize human pluripotent stem cell (hPSC)-derived cardiomyocytes and three-dimensional engineered cardiac tissue constructs to better recapitulate human heart function and drug responses. As these new platforms become increasingly sophisticated and high throughput, the drug screens result in larg ...[more]