Ontology highlight
ABSTRACT:
SUBMITTER: Kuiper HC
PROVIDER: S-EPMC5830112 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Kuiper Heather C HC Wei Na N McGunigale Samantha L SL Vesper Hubert W HW
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20180106
Trans-fatty acids (TFA) are geometric isomers of naturally occurring cis-fatty acids. High dietary TFA intake has been associated with risk factors for cardiovascular disease. However, little is known about TFA levels in humans. To address this data need, we developed and validated a new isotope dilution-gas chromatography-negative chemical ionization-mass spectrometry (ID-GC-NCI-MS) method for quantitation of 27 fatty acids (FA) including 4 major TFA in human plasma, serum, and red blood cells ...[more]