Ontology highlight
ABSTRACT:
SUBMITTER: Porter NT
PROVIDER: S-EPMC5830307 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Porter Nathan T NT Canales Pablo P Peterson Daniel A DA Martens Eric C EC
Cell host & microbe 20170928 4
Capsular polysaccharides (CPSs) play multiple roles in protecting bacteria from host and environmental factors, and many commensal bacteria can produce multiple capsule types. To better understand the roles of different CPSs in competitive intestinal colonization, we individually expressed the eight different capsules of the human gut symbiont Bacteroides thetaiotaomicron. Certain CPSs were most advantageous in vivo, and increased anti-CPS immunoglobulin A correlated with increased fitness of a ...[more]