Ontology highlight
ABSTRACT:
SUBMITTER: Ali MM
PROVIDER: S-EPMC5830406 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Ali Mohamad Moustafa MM Akhade Vijay Suresh VS Kosalai Subazini Thankaswamy ST Subhash Santhilal S Statello Luisa L Meryet-Figuiere Matthieu M Abrahamsson Jonas J Mondal Tanmoy T Kanduri Chandrasekhar C
Nature communications 20180228 1
Despite improvement in our understanding of long noncoding RNAs (lncRNAs) role in cancer, efforts to find clinically relevant cancer-associated lncRNAs are still lacking. Here, using nascent RNA capture sequencing, we identify 1145 temporally expressed S-phase-enriched lncRNAs. Among these, 570 lncRNAs show significant differential expression in at least one tumor type across TCGA data sets. Systematic clinical investigation of 14 Pan-Cancer data sets identified 633 independent prognostic marker ...[more]