Ontology highlight
ABSTRACT:
SUBMITTER: Gialitakis M
PROVIDER: S-EPMC5831049 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Gialitakis Manolis M Tolaini Mauro M Li Ying Y Pardo Mercedes M Yu Lu L Toribio Ana A Choudhary Jyoti S JS Niakan Kathy K Papayannopoulos Venizelos V Stockinger Brigitta B
Stem cell reports 20171026 5
The transcriptional program of early embryonic development is tightly regulated by a set of well-defined transcription factors that suppress premature expression of differentiation genes and sustain the pluripotent identity. It is generally accepted that this program can be perturbed by environmental factors such as chemical pollutants; however, the precise molecular mechanisms remain unknown. The aryl hydrocarbon receptor (AHR) is a widely expressed nuclear receptor that senses environmental st ...[more]