Evolutionary stability of antibiotic protection in a defensive symbiosis.
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ABSTRACT:
SUBMITTER: Engl T
PROVIDER: S-EPMC5834716 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Publications
Evolutionary stability of antibiotic protection in a defensive symbiosis.
Engl Tobias T Kroiss Johannes J Kai Marco M Nechitaylo Taras Y TY Svatoš Aleš A Kaltenpoth Martin M
Proceedings of the National Academy of Sciences of the United States of America 20180214 9
The increasing resistance of human pathogens severely limits the efficacy of antibiotics in medicine, yet many animals, including solitary beewolf wasps, successfully engage in defensive alliances with antibiotic-producing bacteria for millions of years. Here, we report on the in situ production of 49 derivatives belonging to three antibiotic compound classes (45 piericidin derivatives, 3 streptochlorin derivatives, and nigericin) by the symbionts of 25 beewolf host species and subspecies, spann ...[more]
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