Ontology highlight
ABSTRACT:
SUBMITTER: Yang X
PROVIDER: S-EPMC5835949 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Yang Xinglong X Dang Yan Y Lou Jinli J Shao Huawu H Jiang Xingyu X
Theranostics 20180204 5
<b>Rationale:</b> Rapid and facile detection of pathogenic bacteria is challenging due to the requirement of large-scale instruments and equipment in conventional methods. We utilize D-amino acid as molecules to selectively target bacteria because bacteria can incorporate DADA in its cell wall while mammalian cells or fungi cannot. <b>Methods:</b> We show a broad-spectrum bacterial detection system based on D-amino acid-capped gold nanoparticles (AuNPs). AuNPs serve as the signal output that we ...[more]